Chemistry is all around us
It impacts everything we can see, touch, smell
Our faculty provide teaching and research expertise in all major areas of Chemistry
Please Note: Change of Webmaster for Chemistry Department Website: as of the end of February 2019 Professor Qingfeng Ge will take over responsibility as webmaster for the Department website.
The Department offers weekly seminars by faculty from departments throughout the United States and beyond describing the latest advances in their fields.
Departmental Seminars are held in the Van Lente Auditorium (Neckers 240) at 4:00 pm unless otherwise indicated below.
Speaker: Professor Thomas Theis, North Carolina State University
Title: Hyperpolarization Chemistry and Spin Physics for Next-Generation Biosensing
Abstract: Magnetic resonance is an indispensable tool for diverse science, ranging from the most fundamental spin physics and chemistry, probed by NMR spectroscopy, to everyday clinical imaging performed by MRI. However, magnetic resonance signals and the required nuclear spin polarization remain weak even in magnetic fields of superconducting magnets. Only about 1 in 100,000 spins aligns with the magnetic field. Accordingly, NMR and MRI are cherished for their molecular specificity and contrast rich images, but suffer from very low sensitivity. To overcome this limitation, we develop hyperpolarization chemistry using para-hydrogen as the quantum mechanical source of spin order to align much larger fractions of spins. NMR and MRI signals are enhanced by up to six orders of magnitude breaking current sensitivity limits. Fundamental spin physics, chemical design and engineering efforts are combined to make hyperpolarization chemistry ubiquitously practical. Specifically, our efforts are geared towards portable NMR devices for metabolic screening, elucidation of biostructures and dynamics at physiological concentrations, as well as in vivo molecular imaging of metabolic pathways.
Materials Technology Center Seminar Series