Matt McCarroll | Chemistry and Biochemistry | SIU

Southern Illinois University



College of Agriculture, Life and Physical Sciences

Matt McCarroll

Professor, Director of the Fermentation Science Institute


Phone: 618-453-6475
Fax: 618-453-6408

Research in the McCarroll Group involves the application of analytical chemistry to solve complex chemical problems with an emphasis in the area of molecular spectroscopy. Current investigations include systems involving molecular and chiral recognition. We also have an interest in the development of fluorescent sensors and pseudostationary phases for use in micellar capillary electrophoresis (MCE). The primary techniques used in our laboratory include steady-state and time-resolved (ps) fluorescence spectroscopy, capillary electrophoresis and fluorescence polarization. 

Dr. McCarroll is the founding director of the Fermentation Science Institute


B.S., B.A., Appalachian State University
Ph.D., University of Idaho
Postdoctoral Associate, Louisiana State University

Selected Publications

"Cycloalkyl-AminoMethylRhodamines: pH Dependent Photophysical Properties Tuned by Cycloalkane Ring Size", Chuangjun Liu, Quinn A. Best, Brian Suarez, Jack Pertile, Matthew E. McCarroll, Colleen N. Scott, J. Fluoresc., 2015 [accepted].

"Hierarchical structures produced using unbalanced magnetron sputtering for photocatalytic degradation of Rhodamine 6G dye", Kyriaki Polychronopoulou, Samir M. Aouadi, Ben Sirota, Darcy S. Stone, Lichang Wang, Punit Kohli, Matthew E. McCarroll, J. Nanoparticle Res., 2013, [submitted].

 "AnilinoMethylRhodamines as Sensitive Fluorescent Probes for Optical Measurements of pH", Quinn A. Best, Chuangjun Liu, Paul D. van Hoveln, Matthew E. McCarroll, Colleen Scott, J. Org. Chem., 2013, 78(20), 10134-10143.

  “A pH Dependent Si-Fluorescein Hypochlorous Acid Fluorescent Probe: Spiro-Cyclic Ring Opening and Excess HOCl Induced Chlorination”, Quinn A. Best, Narsimha Sattenapally, Daniel J. Dyer, Colleen Scott, and Matthew E. McCarroll, J. Am. Chem. Soc., 2013, 135(36), 13365-13370.

“Detection of Protein Targets with Fluorescence Anisotropy”, Lin Wang, Brendan Clifford, Lacey Starkey, Luke Tolley, and Matthew E. McCarroll, J. Fluorescence., 2013, 23(5), 881-888.

“Bismuth Oxide photocatalytic nanostructures produced by magnetron sputtering deposition”, Ben Sirora, Julia Reyes-Cuelar, Punit Kohli, Lin Wang, Matthew McCarroll, Samir Aouadi; J. Thin Solid Films, 2012,520(19), 6118-6123.

“Molecular Fluorescence, Phosphorescence, and Chemiluminescence Spectrometry”, Anal. Chem., Susmita Das, Aleeta M. Powe, Gary A. Baker, Bertha Valle, Bilal El-Zahab, Herman O. Sintin, Mark Lowry, Sayo O. Fakayode, Matthew E. McCarroll, Gabor Patonay, Min Li, Maxwell L. Geng, and Isiah M. Warner, Anal. Chem., 2012, 84(2), 597-625.

“Utilization of sorghum bagasse hydrolysates for producing microbial lipids”, Tianyu Tang, Arosha Loku Umagiliyage, Thara Siddaramu, Matt McCarroll, Ruplal Choudhary, and Yanna Liang, Appl. Energy, 2012, 91(1), 451-458.

"Molecular Fluorescence, Phosphorescence, and Chemiluminescence Spectrometry”, Aleeta M. Powe, Susmita Das, Mark Lowry, Bilal El-Zahab, Sayo O. Fakayode, Maxwell L. Geng, Gary A. Baker, Lin Wang, Matthew E. McCarroll, Gabor Patonay, Min Li, Mohannad Aljarrah, Sharon Neal and Isiah M. Warner,  Anal. Chem., 2010, 82 (12),pp4865–4894.

“Design and Investigation of a Series of Rhodamine-Based Fluorescent Probes for Optical Measurements of pH”, Quinn A. Best, Ruisong Xu, Matthew E. McCarroll, Lichang Wang, Daniel J. Dyer, Org. Lett., 2010, 12(14), p3219-3221.

“Computational Studies on Response and Binding Selectivity of Fluorescence Sensors”, George A. Hudson, Lei Cheng, Jiamei Yu, Yong Yan, Daniel J. Dyer, Matthew E. McCarroll, and Lichang Wang, J. Phys. Chem. B, 2010, 114 (2), pp 870–876.

“DIABLA: A New Screening Method for the Discovery of Protein Targets”, Robbie Montgomery, Hanna Shay, Matthew McCarroll, and Luke Tolley, J. Proteome Research, 2008, 7(10), 4594-4597.

“Molecular Fluorescence, Phosphorescence, and Chemiluminescence Spectrometry”, Lowry, Mark; Fakayode, Sayo O.; Geng, Maxwell L.; Baker, Gary A.; Wang, Lin; McCarroll, Matthew E.; Patonay, Gabor; Warner, Isiah M., Anal. Chem., 2008, 80(12), 4551-4574.

“Chiral Recognition of 1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate Using Fluorescence Anisotropy”, Yafei Xu and Matthew E. McCarroll, J. Photochem. Photobiol. A: Chemistry, 2007, 187(2-3), 139-145.

"Characterization of Chiral Interactions using Fluorescence Anisotropy" Irene W. Kimaru, Yafei Xu, and Matthew McCarroll, Anal. Chem., 2006, accepted.

“Modulating Fluorescence Resonance Energy Transfer in Conjugated Liposomes”, Xuelian Li, Matthew McCarroll, and Punit Kohli, Langmuir, 2006, accepted.

"Chiral Recognition and Behavior of [1,1'-Binaphthalene]-2,2'-diol in Aqueous Solution by Fluorescence Spectroscopy", Yafei Xu and Matthew E. McCarroll, J. Photochem. Photobiol. A: Chem., 2006, 178, 50-56.

“Evaluation of Chiral Recognition in Cyclodextrins using Fluorescence Anisotropy”, McCarroll, M. E., Irene Kimaru, and Yafei Xu, Abderrazzak Douhal, Ed., Elsevier: Oxford, 2006 (in production) [invited contribution]

"Fluorescence Anisotropy as a Method to Examine Thermodynamics of Enantioselectivity", Yafei Xu and Matthew E. McCarroll, J. Phys. Chem. B, 2005, 109, 8144-8152.]

"Determination of Enantiomeric Composition by Fluorescence Anisotropy", Yafei Xu and Matthew E. McCarroll, J. Phys. Chem. A, 2004, 108, 6929-6932.

"Fluorescence Anisotropy as a Measure of Chiral Recognition", Matthew E. McCarroll, Feresteh Haddadian, and Isiah M. Warner, J. Am. Chem. Soc., , 123(13); 3173-3174.